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Исследования

В лаборатории биомолекулярного ЯМР в настоящее время работают над следующими проектами:

  • Cytoplasmic domain of mucin 1: structural preferences, dynamics, and interactions with pharmaceutically active molecules
  • Development of new solid-state NMR experiments for investigation of protein structure and dynamics: a synergy with liquid-state spectroscopy
  • Activation of rhodopsin: insight from 13C-13C distances in retinal chromophore as measured by solid-state NMR experiments
  • Binding of intrinsically disordered proteins to their folded targets: the effect of enthalpy-entropy compensation
  • Improving NMR structures via state-of-art unconstrained MD simulations