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Histone H4 tails in nucleosomes: a fuzzy interaction with DNA

Опубликовано: 24.02.2021

Sevastyan O. Rabdano, Matthew D. Shannon, Sergei A. Izmailov, Nicole Gonzalez Salguero, Mohamad Zandian, Rudra N. Purusottam, Michael G. Poirier, Nikolai R. Skrynnikov and Christopher P. Jaroniec

https://doi.org/10.1002/anie.202012046

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Стажировка Ольги Рогачевой в институте полимеров им. Макса Планка

Опубликовано: 17.06.2020

Поздравляем Ольгу Рогачеву с победой в конкурсе СПбГУ и DAAD «Дмитрий Менделеев» и стажировкой в институте полимеров им. Макса Планка!

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Crystal structure of the SH3 domain of growth factor receptor-bound protein 2

Опубликовано: 29.05.2020

Bolgov, A., Korban, S., Luzik, D., Zhemkov, V., Kim, M., Rogacheva, O., & Bezprozvanny, I. Crystal structure of the SH3 domain of growth factor receptor-bound protein 2. Acta Crystallographica Section F: Structural Biology Communications, 76(6), 263-270, 2020.

This study presents the crystal structure of the N-terminal SH3 (SH3N) domain of growth factor receptor-bound protein 2 (Grb2) at 2.5 Å resolution. Grb2 is a small (215-amino-acid) adaptor protein that is widely expressed and involved in signal transduction/cell communication. The crystal structure of full-length Grb2 has previously been reported (PDB entry 1gri). The structure of the isolated SH3N domain is consistent with the full-length structure. The structure of the isolated SH3N domain was solved at a higher resolution (2.5 Å compared with 3.1 Å for the previously deposited structure) and made it possible to resolve some of the loops that were missing in the full-length structure. In addition, interactions between the carboxy-terminal region of the SH3N domain and the Sos1-binding sites were observed in the structure of the isolated domain. Analysis of these interactions provided new information about the ligand-binding properties of the SH3N domain of Grb2.

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Structural and dynamic origins of ESR lineshapes in spin-labeled GB1 domain: the insights from spin dynamics simulations based on long MD trajectories

Опубликовано: 22.01.2020

Izmailov, S.A, Rabdano, S.O., Hasanbasri, Z., Podkorytov, I.S., Saxena, S., Skrynnikov, N.R. Structural and dynamic origins of ESR lineshapes in spin-labeled GB1 domain: the insights from spin dynamics simulations based on long MD trajectories. Scientific Reports 2020.

DOI: 10.1038/s41598-019-56750-y

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Molecular Dynamics model of peptide-protein conjugation: case study of covalent complex between Sos1 peptide and N-terminal SH3 domain from Grb2

Опубликовано: 26.12.2019

Luzik, D.A., Rogacheva, O.N., Izmailov, S.A., Indeykina, M.I., Kononikhin, A.S., Skrynnikov, N.R. Molecular Dynamics model of peptide-protein conjugation: case study of covalent complex between Sos1 peptide and N-terminal SH3 domain from Grb2. Scientific Reports 2019, 9(1).

DOI: 10.1038/s41598-019-56078-7

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Joint 12-th EBSA 10-th ICBP-IUPAP Biophysics Congress, Madrid, Spain

Опубликовано: 20.07.2019

Севастьян Рабдано принял участие в биофизическом конгрессе Ассоциации Европейских Биофизических Сообществ с устным докладом «Histone tails in nucleosome: fuzzy interaction with DNA». Конференция прошла 20-24 июля 2019 г. в Мадриде.

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Luminescent Complexes of the Trinuclear Silver(I) and Copper(I) Pyrazolates Supported with Bis(diphenylphosphino)methane

Опубликовано: 19.06.2019

Titov, A. A., Filippov, O. A., Smol’yakov, A. F., Godovikov, I. A., Shakirova, J. R., Tunik, S. P., Podkorytov, I. S. & Shubina, E. S. Luminescent Complexes of the Trinuclear Silver(I) and Copper(I) Pyrazolates Supported with Bis(diphenylphosphino)methane. Inorg. Chem. 58, 8645–8656 (2019).

DOI: 10.1021/acs.inorgchem.9b00991

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16th International School-Conference “Magnetic resonance and its applications, Spinus”, St. Petersburg

Опубликовано: 31.03.2019

Николай Скрынников, Сергей Двинских и Владислав Саликов приняли участие в 16-й международной школе-конференции Spinus 2019, которая прошла 31 марта – 5 апреля 2019 г. в Репино.

Николай Скрынников представил лекцию «When Molecular Dynamics met NMR (and various other experimental methods)».

Сергей Двинских представил доклад «Multinuclear dipolar NMR spectroscopy in ionic liquid crystals».

Владислав Саликов представил доклад «Protein unfolding (denaturation) as monitored by PFG NMR measurements of translational diffusion».

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Multiplet-Matched Filtering of 103Rh Signal Using Information Contained in 31P Spectrum of AA´xXX´x 31P–103Rh Spin System

Опубликовано: 10.10.2018

Podkorytov, I. S., Cherkasova, T. G., Kayfadzhyan, E. A. & Varshavsky, Yu. S. Multiplet-Matched Filtering of 103Rh Signal Using Information Contained in 31P Spectrum of AA′XX′ 31P–103Rh Spin System. Appl Magn Reson 50, 563–568 (2019).

DOI: 10.1007/s00723-018-1083-1

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13C NMR spectrum of crystalline [Rh(Acac) (CO)2]: A contribution to the discussion on [Rh(Acac) (CO)2] molecular structure in the solid state

Опубликовано: 11.08.2018

Varshavsky, Yu. S., Cherkasova, T. G., Galding, M. R., Korlyukov, A. A., Podkorytov, I. S., Gindin, V. A., Smirnov, S. N., Mazur, A. S. & Rubaylo, A. I. 13C NMR spectrum of crystalline [Rh(Acac) (CO)2]: A contribution to the discussion on [Rh(Acac) (CO)2] molecular structure in the solid state. Journal of Organometallic Chemistry 874, 70–73 (2018).

DOI: 10.1016/j.jorganchem.2018.08.009

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