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Posts tagged ‘Izmailov’

A new structural arrangement in proteins involving lysine NH3+ group and carbonyl

Posted: 27.11.2017

Rogacheva, O. N.; Izmailov, S. A.; Slipchenko, L. V.; Skrynnikov, N. R. A New Structural Arrangement in Proteins Involving Lysine NH3 + Group and Carbonyl. Scientific Reports 20177 (1).

DOI: 10.1038/s41598-017-16584-y.

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Onset of disorder and protein aggregation due to oxidation-induced intermolecular disulfide bonds: case study of RRM2 domain from TDP-43

Posted: 11.09.2017

Rabdano, S. O.; Izmailov, S. A.; Luzik, D. A.; Groves, A.; Podkorytov, I. S.; Skrynnikov, N. R. Onset of Disorder and Protein Aggregation due to Oxidation-Induced Intermolecular Disulfide Bonds: Case Study of RRM2 Domain from TDP-43. Scientific Reports 20177 (1), 11161.

DOI: 10.1038/s41598-017-10574-w.

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New linear interaction between charged lysine side chain and carbonyl group in protein structures

Posted: 08.09.2017

Rogacheva, O. N.; Izmailov, S. A.; Slipchenko, L. V.; Skrynnikov, N. R. Non-Native Disulfide Bridges in Protein-Peptide Complex and in Protein Homodimers Trigger Unfolding and Aggregation. The FEBS Journal 2017284 (Suppl. 1), 311.

DOI: 10.1111/febs.14174.

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Local and global dynamics of intrinsically disordered proteins: a case study of H4 histone tail

Posted: 08.09.2017

Kaempf, K.; Rabdano, S. O.; Izmailov, S. A.; Groves, A.; Podkorytov, I. S.; Skrynnikov, N. R. Local and Global Dynamics of Intrinsically Disordered Proteins: A Case Study of H4 Histone Tail. The FEBS Journal 2017, 284 (Suppl. 1), 95.

DOI: 10.1111/febs.14171.
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Simple MD-based model for oxidative folding of peptides and proteins

Posted: 24.08.2017

Izmailov, S. A.; Podkorytov, I. S.; Skrynnikov, N. R. Simple MD-Based Model for Oxidative Folding of Peptides and Proteins. Scientific Reports 20177 (1).

DOI: 10.1038/s41598-017-09229-7.

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Slow Conformational Exchange and Overall Rocking Motion in Ubiquitin Protein Crystals

Posted: 27.07.2017

Kurauskas, V.; Izmailov, S. A.; Rogacheva, O. N.; Hessel, A.; Ayala, I.; Woodhouse, J.; Shilova, A.; Xue, Y.; Yuwen, T.; Coquelle, N.; Colletier, J.-P.; Skrynnikov, N. R.; Schanda, P. Slow Conformational Exchange and Overall Rocking Motion in Ubiquitin Protein Crystals. Nature Communications 20178 (1).

DOI: 10.1038/s41467-017-00165-8.

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Conference of Institute of Translational Biomedicine of SPbSU “Actual Problems of Translational Biomedicine – 2017”

Posted: 16.07.2017

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Nikolai Skrynnikov, Ivan Podkorytov, Dmitry Luzik, Olga Rogacheva, Sevastyan Rabdano, Sergei Izmailov, Ali Shaban and Oleg Mikhailovsky attended the conference of Institute of Translational Biomedicine of SPbSU “Actual Problems of Translational Biomedicine – 2017”, St. Petersburg.

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BioHack 2017

Posted: 05.03.2017

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Sevastyan Rabdano, Sergei Izmailov and Dmitri Luzik took part in bioinformatics hackathon BioHack 2017.

Sergei Izmailov was a leader of a team that worked on the project “Identification of oncogene proteins as targets for covalently binding peptides”.

Dmitry Luzik was in team that worked on the project “Interactome of human proteoforms”.

Sevastyan Rabdano was in team that worked on the project “Research of bound states of water molecules at the interfaces of biomolecules”. His team took third place and received award from organizers.

 

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Dynamics in protein crystals: insights from MD simulations complement new solid-state NMR and X-ray data

Posted: 03.09.2016

O. N. Rogacheva , S. A. Izmailov , V. Kurauskas , A. Shilova , P. Ma, Y. Xue, N. Coquelle, J. D. Haller, T. Yuwen, I. Ayala, A. Hessel, J. Woodhouse, O. Mikhailovskii, D. Willbold, J. Colletier, N. R. Skrynnikov, P. Schanda “Dynamics in protein crystals: insights from MD simulations complement new solid-state NMR and X-ray data” The FEBS Journal 283 (Suppl. 1), 237 (2016).

DOI: 10.1111/febs.13808

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XXXVIII Finnish NMR Symposium

Posted: 13.06.2016

Finnish NMR symposium

Nikolai Skrynnikov, Ivan Podkorytov, Sergei Izmailov, Olga Rogacheva, Kerstin Kaempf and Sevastyan Rabdano attended XXXVIII Finnish NMR Symposium, Jyvaskyla, Finland.

Nikolai Skrynnikov presented lecture “Dynamics in Protein Crystals: Insights From MD Simulations Complement New Solid-State NMR And X-Ray Data”.

Kerstin Kaempf presented oral talk “Local and global dynamics of intrinsically disordered proteins: a case study of H4 histone tail“.

Ivan Podkorytov presented poster “Diffusion-filtered experiment to detect flexible portion of protein chain in amyloid fibrils: application to Sup35NM“.

Sergei Izmailov presented poster “Simple MD-based model for oxidative folding of peptides and proteins”.

Olga Rogacheva presented poster “Using molecular dynamics simulation and chemical shift prediction to unravel dynamics in different crystal forms of ubiquitin”.

Sevastyan Rabdano presented poster “Loss of protein stability due to formation of intermolecular disulfide bonds under the effect of oxidative stress: case study of the RRM2 domain from neuropathological protein TDP-43”.

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